Maypracina is a powdered antimicrobial designed to be administered in drinking water or milk. The active ingredient is apramycin (sulfate), an aminoglycoside antibiotic. Maypracina is indicated for treatment of gastrointestinal infections caused by strains of E. coli and Salmonella sensitive to apramycin.
Apramycin is a broad spectrum aminoglycoside antibiotic used in veterinary medicine to treat various infections. It is especially active against Gram-negative bacteria and is commonly used to treat E. coli infections (colibacillosis) in pigs, although it has also been approved for use in other species.
Given its nature, the aminoglycosides are not fat soluble and not absorbed in the intestines, which means they are excreted almost completely without any residue in the animal: approximately 97% is eliminated in the animal’s feces.
Advantages of Maypracina
01
It is compatible with other medications administered orally in drinking water
Like colistin sulfate and enrofloxacin.
02
Low antimicrobial resistance
03
Stable in drinking water after 24 hours
04
Stable and soluble in various types of water
Hard and soft pH 4.5 – 9.
05
Can be stored at room temperature.
Responsible use of antibiotics
Veterinary medications, including antibiotics, play a key role in managing animal health. Farmers, veterinarians and anyone involved in animal care have the responsibility to look out for their health and wellbeing, which requires access to the right tools to do so. We must promote responsible use of antibiotics to treat bacterial infections in livestock and pets. Responsible use means administering precise doses for the period indicated, only when necessary and always with a prescription from a veterinarian.
Proper management of veterinary drugs is part of a comprehensive approach geared towards minimizing diseases, which includes measures like: farm biosecurity, proper facilities, optimal hygiene, balanced nutrition, regular monitoring of animal health and wellbeing, including vaccination when necessary, and a comprehensive healthcare plan.
Hayer et al. (2020) Prevalence and trend analysis of antimicrobial resistance in clinical Escherichia coli isolates collected from diseased pigs in USA between 2006- 2016. Transbound Emerg Dis.
Fairbrother J.M., Nadeau E. (2006) Escherichia coli: on-farm contamination of animals. Rev Sci Tech. 25(2):555-69. PMID: 17094697.